Sensitization to Drugs
نویسندگان
چکیده
منابع مشابه
First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians.
Behavioral sensitization in mammals, including humans, is sensitive to factors such as administration route, testing environment, and pharmacokinetic confounds, unrelated to the drugs themselves that are difficult to eliminate. Simpler animals less susceptible to these confounding influences may be advantageous substitutes for studying sensitization. We tested this hypothesis by determining whe...
متن کاملSkin Sensitization to Remiderm and Cross-sensitization to Hydroxyquinoline Compounds.
EDITSHAL and usually, as in the present case, constructional apraxia will be detected with or without ideational apraxia, alexia, or sensory agnosia. Interpretation of Gerstmann's syndrome as an easily demonstrated and memorable pointer to diffuse cerebral damage accords well with this case, where there is no reason to suspect a highly focal lesion. Gerstmann's syndrome does not seem to have be...
متن کاملSensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity.
BACKGROUND The transmembrane receptor Fas, together with its protein-binding partner (Fas ligand), is a key regulator of programmed cell death (i.e., apoptosis). Fas and Fas ligand also influence the ability of cytotoxic T lymphocytes and natural killer cells to eliminate tumor cells. However, by inducing apoptosis in activated T cells, the Fas/Fas ligand system may protect some tumor cells fro...
متن کاملAbility of vasoconstrictor drugs to cause adrenal medullary discharge after "sensitization" by ganglion stimulating agents.
HAAS and Goldblatt 1 reported that infusion of DMPP (l,l-dimethyl~t-phenylpiperazinium iodide), a ganglion stimulating agent, causes increase of pressor responsiveness to angiotensin. The experiments reported here reveal that, instead of enhancement of the direct effect of angiotensin on the cardiovascular S3'Stem, the larger responses that follow treatment with DMPP are due to adrenal discharg...
متن کاملAntiulcer drugs promote oral sensitization and hypersensitivity to hazelnut allergens in BALB/c mice and humans.
BACKGROUND Hazelnut allergy can be a consequence of sensitization to cross-reactive pollen, especially from the Fagales family. However, severe allergic reactions after ingestion of hazelnuts without associated pollen allergy have been reported. In these cases, oral sensitization by hazelnut ingestion is plausible. OBJECTIVE We have reported that antiulcer drugs promote oral sensitization to ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1971
ISSN: 0021-9746
DOI: 10.1136/jcp.24.1.91-c